草泥馬成人類救星? 研究:駱馬抗體可殲滅新冠肺炎病毒

https://pets.ettoday.net/news/1696331?from=mweb-newsshare-line 草泥馬! 真的假的啊?
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Pei-Chi Lo mark this message contains personal perspective
originally written by Pei-Chi Lo
■此研究確實存在,是2020年3月28日置於bioRxiv的文章:

①該文主張,llama(美洲駝,俗稱草泥馬)的單域抗體可強力中和假型的MERS、SARS冠狀病毒,阻斷病毒與受體結合。

②再透過的SARS、本次COVID-19疫情的冠狀病毒間的交叉反應,推論其對COVID-19的病毒亦有相同阻斷受體結合的能力,可能可用於疫情期間治療的研發。

■但須留意,bioRxiv平台有提醒,這是一篇預印本文章(preprint),尚未經同儕審查,不應作為既定事實報導;在文章通過審查刊登於正式期刊前,建議謹慎看待其內容。

Opinion Sources

此研究的預印本全文-Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies:
https://www.biorxiv.org/content/10.1101/2020.03.26.010165v1

Nature對此文的介紹-請見「1 April 」段:
https://www.nature.com/articles/d41586-020-00502-w

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies

New Results , Dorien De Vlieger, Kizzmekia S. Corbett, Gretel M. Torres, Wander Van Breedam, Kenny Roose, Loes van Schie, VIB-CMB COVID-19 Response Team, Markus Hoffmann, Stefa

https://www.biorxiv.org/content/10.1101/2020.03.26.010165v1

Pick of the coronavirus papers: Intensive testing finds a small town’s many silent infections

A human cell (blue; artificially coloured) infected with SARS-CoV-2 (yellow).Credit: NIAID/NATIONAL INSTITUTES OF HEALTH/SPL Fresh findings about SARS-CoV-2 and the disease it causes.23 April — I

https://www.nature.com/articles/d41586-020-00502-w
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